Ultra-Sensitive Immunoassays

Ultra-sensitive immunoassays (those in sub picomolar range), provide an ability to accurately and precisely quantify low levels of biomarkers as well as bio therapeutics (PK samples), with robustness .

The Singulex® system couples proprietary digital Single Molecule Counting (SMC™) technology with microparticle-based immunoassays to provide higher sensitivity over traditional immunoassays, such as ELISA platforms.

Smithers Avanza, a GLP and CLIA-certified laboratory has developed and validated assays and analyzed samples for PK and Biomarkers on the Singulex ERENNA® platform.

We have fully validated the Singulex ERENNA® and the interface to the Watson LIMS™ in a GLP environment.

This has the following advantages:

  • Data regression, raw data storage are within Watson LIMS™
  • Can optimize standard curve as needed
  • Do not need 12 point curve
  • During development can have multiple curves on the plate
  • Greater sample capacity
  • Can select one of three output as raw data source
  • Full chain of custody for samples