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Repeat Dose Toxicity Studies of 3-Bromopyruvate in Dogs Following Intrahepatic Artery and Intraperitoneal Infusion

Godin, C.S., Engelke, K.E., and Geschwind, J.  Repeat Dose Toxicity Studies of 3-Bromopyruvate in Dogs Following Intrahepatic Artery and Intraperitoneal Infusion.American College of Toxicology Meeting, Orlando, FL, November 2014.

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Reproductive and Developmental Toxicity Testing

Examination of the Extended One-Generation Reproductive Toxicity Study Guideline
Authors:Shakil A Saghir, Ph.D. and Michael A Dorato, Ph.D.

This whitepaper discusses ways to make the EOGRTS guideline easier to follow; suggesting procedures to select relevant doses, and monitor the systemic exposure at different life stages for better interpretation of the data.