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Toxicologic Assessment of Pharmaceutical and Biotechnology Products in Principles and Methods of Toxicology

Dorato M. A., McMillian, C. L., Williams, T. M. 2014. Toxicologic Assessment of Pharmaceutical and Biotechnology Products in Principles and Methods of Toxicology 6th edition, Hayes, A. W. and Kruger, C. L. editors, Chapter 8, pp. 333 – 366.

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Reproductive and Developmental Toxicity Testing

Examination of the Extended One-Generation Reproductive Toxicity Study Guideline
Authors:Shakil A Saghir, Ph.D. and Michael A Dorato, Ph.D.

This whitepaper discusses ways to make the EOGRTS guideline easier to follow; suggesting procedures to select relevant doses, and monitor the systemic exposure at different life stages for better interpretation of the data.