Toxicology

Smithers Avanza Toxicology Services, a division of Smithers Avanza, is a GLP-compliant, AAALAC-accredited, USDA-registered, OLAW-assured and DEA-licensed facility located in Gaithersburg, Maryland.  Our Team collaborates with clients to plan and conduct safety assessment studies for pharmaceuticals (small molecules and biologics), nutraceuticals, vaccines, agro and industrial chemicals.

We are experienced in establishing Margin of Safety (MoS), No-Observed-Adverse-Effect Level (NOAEL) and No-Observed-Effect Level (NOEL) in preclinical studies.

Our vivarium houses rodents, rabbits, canines, non-human primates, and swine and includes surgery and necropsy suites and analytical and clinical chemistry laboratories.  Studies support our clients’ short- and long-term research efforts.

Smithers Avanza Toxicology Services is proud of our standards of animal care and committed to the welfare of our study animals.  We have successfully conducted over 1600 preclinical studies, ranging in duration from less than 1 week to 2 years or longer.

Our studies are conducted to the highest scientific standards and in compliance with the FDA and international regulatory requirements and client requirements.  We also offer a proven track record of on‑time delivery of results and reports.  All of our client interactions are conducted under a mutually acceptable confidentiality agreement (CDA) as we recognize that your proprietary information is your valuable property.

The Smithers Avanza Toxicology Services Approach

  • Collaborative approach to study design and execution
  • Rapid communication of findings and updates
  • Planning/project initiation meetings
  • Scientific and business integrity
  • Operational excellence
  • On-time delivery of high-quality reports