Toxicology Services Facility

The Smithers Avanza Toxicology Services AAALAC accredited toxicology facility is staffed with experienced and dedicated people specializing in animal handling and husbandry, sanitation, dosing techniques, sample and data collection, necropsy, and dose formulation/analysis. The site is routinely inspected by the FDA, USDA, AAALAC, as well as many of our sponsor’s Quality Assurance Units and scientific teams.

Facility Highlights

  • 30,000 square feet with 35 animal rooms
  • Controlled assess and on site security systems
  • Automated environmental monitoring system (REES)
  • Provantis™ data acquisition software (Dispense, In-life, Clinical Pathology, and Pathology modules integrated)
  • Ponemah™ data acquisition software (telemetry and respiration parameters)
  • Empower 2 data acquisition software (HPLC)
  • Reverse osmosis automatic watering systems
  • Redundant cage wash facilities
  • Surgery suite
  • Necropsy suites
  • Histology and developmental and reproductive toxicology areas
  • Formulations, Dose Analysis, and Clinical Chemistry laboratories
  • Autoclave

Our laboratory is designed to accommodate a wide variety of projects. Experienced and dedicated staff specializes in a wide variety of dosing techniques, surgical procedures, sample collection, necropsy procedures, formulation and dose analysis, and clinical chemistry analyses. The temperature, humidity, and lighting in the animal rooms are monitored continuously to comply with all relevant regulatory requirements, as are the chemical and biological sample storage units. The HVAC system provides HEPA-filtered air and maintains room air changes in accordance with the Guide for the Care and Use of Laboratory Animals. The facility is supported by back-up power, equipment is properly maintained and calibrated, and our systems are fully validated.